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Breed Information

  • Different breeds have a genetic predisposition for different heart diseases
    • There are certain genes that have been present in certain breeds, over countless generations that cause certain diseases
      • Some genes remain hidden in the background, but are present (genotype)
      • Some genes become expressed physically, causing disease (phenotype)
      • These genes can be passed on from generation to generation
        • They can be very dominant where only one parent with the gene can pass on the disease (autosomal dominant)
        • They can be recessive, where it takes two parents with the gene to pass on disease (autosomal recessive)
        • There can be multiple genes that have to be in the right combination to pass on (polygenic)
  • Breed Dispositions by Disease
    • Congenital Defects (from birth)
      • Patent Ductus Arteriosus (PDA) (see PDA page)
        • Bichon Frise
        • Chihuahuas
        • Cocker Spaniels
        • Collies
        • English Springer Spaniels
        • German Shepherds
        • Keeshonds,
        • Labrador Retrievers
        • Maltese
        • Pomeranians
        • Poodles
          • familial, probably polygenic
        • Shetland Sheepdogs
        • Welsh Corgis
        • Yorkshire Terriers
      • Pulmonic Stenosis (PS) (see PS page)
        • Bassets
        • Beagles
          • familial, probably polygenic
        • Bull Mastiffs
        • Chihuahuas
        • Chows
        • Cocker Spaniels
        • English Bulldogs
          • often due to a coronary artery abnormality
        • Fox terriers
        • Keeshonds
        • Mastiffs
        • Miniature Schnauzers
        • Newfoundlands
        • Samoyed
        • West Highland White terriers
      • Subaortic Stenosis (SAS) (see SAS page)
        • Boxers
        • Bouvier des Flandres
        • German Shepherds
        • Golden Retrievers
        • Newfoundland
          • familial, probably polygenic
        • Rottweilers
      • Tricuspid Dysplasia (TVD) (see TVD page)
        • German Shepherds
        • Great Danes
        • Irish Setters
        • Labrador Retrievers
        • Old English Sheepdogs
      • Ventricular Septal Defects (VSD)
        • English Springer Spaniel
      • Uncommon Congenital Defects
        • Atrial Septal Defects (ASD)
          • Boxers
          • cats
          • Doberman Pinschers
          • Old English Sheepdogs
          • Samoyeds
          • Standard Poodles
        • Mitral Valve Dysplasia (the congenital form of mitral valve disease) (see MI page)
          • Afghan Hounds
          • cats
          • German Shepherds
          • Great Danes
        • Right to Left Patent Ductus Arteriosus (reverse PDA)
        • Tetralogy of Fallot
          • Keeshonds
    • Acquired Diseases (develop over time)
      • Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC, Boxer cardiomyopathy) (see ARVC page)
      • Dilated Cardiomyopathy (DCM) (see DCM page)
        • American Cocker Spaniels
        • Boxers
        • Doberman Pinschers
        • Great Danes
        • Irish Wolfhounds
        • Mastiffs
        • Newfoundlands
        • Portuguese Water Dogs
      • Hypertrophic Cardiomyopathy (HCM) (see HCM page)
        • American shorthair
        • British shorthairs
        • Maine coon cat
          • autosomal dominant
        • Persian
        • Ragdoll
      • Mitral Valve Disease (mitral insufficiency (MI), mitral regurgitation (MR), chronic degenerative valve disease (CVD), myxomatous degeneration or endocardiosis) (see MI page)
        • Cavalier King Charles Spaniels (CKCS)
          • familial, probably polygenic
        • Chihuahuas
        • Dachshunds
        • Maltese
        • Papillion
        • Poodles